BIOENGR C131

Nanopore Sensing

Bioengineering · 4 units · Undergraduate upper division (100-199)

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Analysis of sensors based on measurements of fluctuating ionic conductance through artificial or protein nanopores. Physics of pore conductance. Applications to single molecule detection and DNA sequencing. Review of current literature and technological applications. History and instrumentation of resistive pulse sensing, theory and instrumentation of electrical measurements in electrolytes, nanopore fabrication, ionic conductance through pores and GHK equation, patch clamp and single channel measurements and instrumentation, noise issues, protein engineering, molecular sensing, DNA sequencing, membrane engineering, and future directions of field. Concurrently scheduled with course C231.

Letter grading.

Requisites

Official UCLA wording
Requisites: courses 100, 120, Life Sciences 7A, Physics 1A, 1B, 1C.

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Requires

Everything that has to come before this course, not just the courses named in the requisite above.

BIOENGR C131

BIOENGR 100Bioengineering Fundamentals
- MATH 32ACalculus of Several Variables
  - MATH 31ADifferential and Integral Calculusanother path to it
- PHYSICS 1APhysics for Scientists and Engineers: Mechanicsanother path to it
BIOENGR 120Biomedical Transducers

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What this course is a requisite for, and what those courses lead to in turn.

No course in the catalog lists this as a requisite.